Volledige tracklist Guitar Hero 2 bekend
1. Opening Licks
Motley Crue - Shout at the Devil
Danzig - Mother
Cheap Trick - Surrender
Wolfmother - Woman
Spinal Tap - Tonight I'm Gonna Rock You Tonight
2. Amp-Warmers
Kiss - Strutter
Nirvana - Heart-Shaped Box
Police - Message in a Bottle
Van Halen - You Really Got Me
Kansas - Carry on Wayward Son
3. String-Snappers
Foo Fighters - Monkey Wrench
Alice in Chains - Them Bones
Iggy Pop and the Stooges - Search and Destroy
Pretenders - Tattooed Love Boys
Black Sabbath - War Pigs
4. Thrash and Burn
Warrant - Cherry Pie
Butthole Surfers - Who Was in My Room Last Night
Mathew Sweet - Girlfriend
Rolling Stones - Can't You Hear Me Knockin'
Guns N' Roses - Sweet Child O' Mine
5. Return of the Shred
Rage Against the Machine - Killing in the Name Of
Primus - John the Fisherman
Sword - Freya
Thin Lizzy - Bad Reputation
Aerosmtih - Last Child
6. Relentless Riffs
Heart - Crazy on You
Stone Temple Pilots - Tripping on a Hole in a Paper Heart
Stray Cats - Rock This Town
Allman Brothers - Jessica
Jane's Addiction - Stop
7. Furious Fretwork
Anthrax - Madhouse
Living End - Carry Me Home
Lamb of God - Laid to Rest
Reverend Horton Heat - Psychobilly Freakout
Rush - YYZ
8. Face-Melters
Avenged Sevenfold - Beast and the Harlot
Suicidal Tendencies - Institutionalized
Dick Dale - Misirlou
Megadeth - Hangar 18
Lynyrd Skynyrd - Free Bird
De bonustracks en unlockable tracks blijven geheim tot de game ook daadwerkelijk uit is. Dit wil RedOctane in verband met het verrassingselement voor de fans.