| FC Lokomotiv Moskva (RUS) | FC Midtjylland (DEN) | 2-0 | 3-1 |
| ACF Fiorentina (ITA) | FC Groningen (NED) | 1-1 ( 4-3 pen) | 1-1 |
| Bolton Wanderers FC (ENG) | FK Rabotnički (MKD) | 1-0 | 1-1 |
| FC Red Bull Salzburg (AUT) | AEK FC (GRE) | 1-0 | 0-3 |
| FC Rapid Bucureşti (ROU) | 1. FC Nürnberg (GER) | 2-2 | 0-0 |
| FC Metalist Karkhiv (UKR) | Everton FC (ENG) | 2-3 | 1-1 |
| Standard Liège (BEL) | FC Zenit St. Petersburg (RUS) | 1-1 | 0-3 |
| União Leiria (POR) | Bayer 04 Leverkusen (GER) | 1-3 | 3-2 |
| FC BATE Borisov (BLR) | Villarreal CF (ESP) | 0-2 | 1-4 |
| Galatasaray SK (TUR) | FC Sion (SUI) | 5-1 | 2-3 |
| Kayseri Erciyesspor (TUR) | Club Atlético de Madrid (ESP) | 0-5 | 0-4 |
| Girondins de Bordeaux (FRA) | Tampere United (FIN) | 1-1 | 3-2 |
| Panathinaikos FC (GRE) | FC Artmedia Petrzalka (SVK) | 3-0 | 2-1 |
| Odense BK (DEN) | AC Sparta Praha (CZE) | 0-0 (3-4 pen) | 0-0 |
| FC Zürich (SUI) | Empoli FC (ITA) | 3-0 | 1-2 |
| Panionios GSS FC (GRE) | FC Sochaux-Montbéliard (FRA) | 0-1 | 2-0 |
| SK Rapid Wien (AUT) | RSC Anderlecht (BEL) | 0-1 | 1-1 |
| AZ Alkmaar (NED) | FC Paços de Ferreira (POR) | 0-0 | 1-0 |
| Aalborg BK (DEN) | UC Sampdoria (ITA) | 0-0 | 2-2 |
| BK Häcken (SWE) | FC Spartak Moskva (RUS) | 1-3 | 0-5 |
| Sporting Clube de Braga (POR) | Hammarby IF (SWE) | 4-0 | 1-2 |
| Blackburn Rovers FC (ENG) | Athlitiki Enosi Larisas 1964 (GRE) | 2-1 | 0-2 |
| US Città di Palermo (ITA) | FK Mladá Boleslav (CZE) | 0-1 (2-4 pen) | 1-0 |
| AFC Ajax (NED) | NK Dinamo Zagreb (CRO) | 2-3 (nv) | 1-0 |
| Stade Rennais (FRA) | PFC Lokomotiv Sofia (BUL) | 1-2 | 3-1 |
| Club Brugge KV (BEL) | SK Brann (NOR) | 1-2 | 1-0 |
| CF Os Belenenses (POR) | FC Bayern München (GER) | 0-2 | 0-1 |
| FC Dnipro Dnipropetrovsk (UKR) | Aberdeen FC (SCO) | 1-1 | 0-0 |
| Helsingborgs IF (SWE) | sc Heerenveen (NED) | 5-1 | 3-5 |
| PFC CSKA Sofia (BUL) | Toulouse FC (FRA) | 1-1 | 0-0 |
| Hamburger SV (GER) | PFC Litex Lovech (BUL) | 3-1 | 1-0 |
| FC Basel (SUI) | FK Sarajevo (BIH) | 6-0 | 2-1 |
| Vålerenga IF (NOR) | FK Austria Wien (AUT) | 2-2 | 0-2 |
| AIK (SWE) | Hapoel Tel Aviv FC (ISR) | 0-1 | 0-0 |
| Real Zaragoza (ESP) | PAE Aris Thessalonikis (GRE) | 2-1 | 0-1 |
| Elfsborg IF (SWE) | FC Dinamo Bucureşti (ROU) | 0-1 | 2-1 |
| Anorthosis Famagusta (CYP) | Tottenham Hotspur FC (ENG) | 1-1 | 1-6 |
| FC København (DEN) | RC Lens (FRA) | 2-1 (nv) | 1-1 |
| FC Twente (NED) | Getafe CF (ESP) | 3-2 (nv) | 0-1 |
| FK Crvena Zvezda (SRB) | Dyskobolia Grodzisk Wielkopolski (POL) | 1-0 | 1-0 |
De loting voor de groepsfase is aankomende dinsdag.
